Monday 27 February 2012

Nicotinamide protect us from the sun

Nicotinamide


Nicotinamide reportedly increases the endurance of mice, avoids immunosuppression caused by UVA and UVB radiation.Therefore,nicotinamide could protect us from the sun.
Nicotinamide is also reported to be an effective skin whitener in topical application.In additon,nicotinamide also acts a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia.
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Friday 24 February 2012

the uses of Dipyridamole

Dipyridamole
Dipyridamole acts as a thromboxane synthase inhibitor,consequently lowering the levels of TXA2 and  stopping the effects of TXA2 .
Dipyridamole inhibits the cellular reabsorption of adenosine into platelets, red blood cells and endothelial cells cause increasing extracellular concentrations of adenosine.
Dipyridamole also inhibits the enzyme adenosine deaminase from  breaking down normally adenosine into inosine,which leads to further increased levels of extracellular adenosine.
Dipyridamole also inhibits the phosphodiesterase enzymes that normally break down cAMP and/or cGMP ..

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Wednesday 22 February 2012

the description of Betaine

Betaine


A betaine in chemistry is any neutral chemical compound with a positively charged cationic functional group. For example, a quaternary ammonium or phosphonium cation  which bears no hydrogen atom and with a negatively charged functional group such as a carboxylate group which isn't adjacent to the cationic site possibly.Therefore, a betaine  may be a specific kind of zwitterion.
In biological systems, a great many of betaines serve as organic osmolytes, substances synthesised or taken up from the environment by cells for protection against osmotic stress, drought, high salinity or high temperature.

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Monday 20 February 2012

the application of Propionic acid

Propionic acid


Propanoicacid control the growth of mold and some bacteria at the levels between 0.1 and 1% by weight.Therefore, most propanoic acid produced is consumed as a preservative for both animal feed and food for human consumption. For animal feed, it is used either directly or as its ammonium salt. The antibiotic Monensin is added to cattle feed to favor propionibacteria over acetic acid producers in the rumen; this produces less carbon dioxide and feed conversion is better. This application accounts for about half of the world production of propanoic acid. Another major application is as a preservative in baked goods, which use the sodium and calcium salts.
propanoicacid is also useful as an intermediate in the production of other chemicals.Vinyl propionate is also used. In more specialized applications, it is also used to make pesticides and pharmaceuticals. The esters of propanoicacid have fruit-like odors and are sometimes used as solvents or artificial flavorings.

Thursday 16 February 2012

4-(3-Nitrophenyl)morpholine’s Chemical properties


4-(3-Nitrophenyl)morpholine
Morpholine is an organic chemical compound with the chemical formula O (CH2CH2) 2NH. This heterocycle, pictured to the right to offer, both amine and ether functional groups. Due to the amine, morpholine is a base whose conjugate acid is used as morpholinium. For example, neutralization with hydrochloric acid morpholine salt morpholinium chloride.
Morpholine is widely used in organic synthesis. For example, it is a building block in the production of the antibiotic linezolid, the anticancer agent Gefitinib (IRESSA) and the analgesic dextromoramide.
Lead in research and industry, the low cost and the polarity of morpholine to its common use as solvents for chemical reactions.
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Tuesday 14 February 2012

The introduction of Dipyridamole

Dipyridamole
Dipyridamole (trade name Persantine) is a drug, the thrombus formation inhibits chronic and leads to vasodilation given if given at high doses over a short period. Dipyridamole overdose can be treated with aminophylline and reverses its hemodynamic effects (vasodilation). Symptomatic treatment is recommended, possibly with vasopressor drug. Gastric lavage should be considered. Can reverse the administration of xanthine derivatives (eg aminophylline) the hemodynamic effects of dipyridamole overdose. Since dipyridamole is highly protein bound, dialysis is unlikely to be useful.
Dipyridamole was pressure.Dipyridamole pulmonary hypertension without significant decrease in systemic blood pressure and non-medical applications in the laboratory context, such as reducing the inhibition of the cardio virus growth in cell culture.
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Wednesday 8 February 2012

What is 57-Dihydroxy-4-methylcoumarin used for?


57-Dihydroxy-4-methylcoumarin

We know that sun's rays are the  harshest between 10 am and 4 pm. Doctors advise that it is best to stay indoors during this time. It is harmful to bask in the sun for hours at a time. But if you have oily skin and prefer to go outside and soak up some rays of the sun, you can be sure to look forward to a nice, even tan. You don't have to worry about, if you have suntan oils .The oil on your skin keeps it well lubricated and helps to even out the sunlight shining down over your skin. This is a pleasure that people with dry skin are not so fortunate to have. Suntan oils contains a substance called  5,7-Dihydroxy-4-methylcoumarin, which help protect your health.

Mentioned 5,7-Dihydroxy-4-methylcoumarin, it actually have other uses. 5,7-Dihydroxy-4-methylcoumarin is also used as whitening agents in wall paints. Here I share with you about its chemical properties: Its CAS is 2107-76-8 and the molecular formula is C10H8O4.Weight:192.17g/mol.It is slightly water soluble.

 

Tuesday 7 February 2012

Podophyllin is for your choice


Product name:Podophyllin Podophyllin is a drug obtained from the rhizome of the American Mayapple (Podophyllum peltatum), an herbaceous perennial belonging to the natural order Berberidaceae, indigenous in woods in Canada and the United States.
Podophyllin is a resinous powder obtained by precipitating an alcoholic tincture of the rhizome by means of water acidulated with hydrochloric acid. It varies in color from grayish to bright yellow or greenish-brown, the first-named being the purest.Podophyllin resin must be applied by a health professional so that the amount used can be carefully monitored to avoid more serious side effects.
CAS:9000-55-9
Specification:100g/25g/5g
Molecular Formula:W99
Molecular Weight:1693.65g/mol
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Monday 6 February 2012

How to use RNA Marker (0.5 to 9 kb)

RNA Marker (0.5 to 9 kb) consists of RNA transcripts from 0.5 kb to 9 kb,in sizes of 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, and 9 kb.The markers can be denatured with standard procedures, and visualized on Northern blots with labeled lambda RNA sequence.Markers are provided at a concentration of 1mg/ml.Ethidium bromide staining will easily detect 4μg of DNA on a standard agarose gel.
Smaller quantities can be detected with GelStar Nucleic Acid Gel Stain or SYBR® Green II Gel Stain.
RNA Marker (0.5 to 9 kb) can be a difficult molecule to work with and is readily degraded by RNases that are found in a variety of environmental sources, including fingerprints. By minimizing nuclease contamination and ensuring the most stringent quality specifications, Ambion® products succeed in less-than-ideal conditions. This is referred to as "building robustness" into the products and continues to be a primary focus of our product development today.
Specification: 250ul (50ug)
Storage: DEPC treated H20/0.1 mM EDTA

Friday 3 February 2012

Effect of Piperaquine Phosphate

Antimalarial effect of Piperaquine Phosphate is similar to chloroquine. Stored in the liver after oral absorption, and slow release into the blood, the role of long-term prevention. Mainly used for the inhibition of the symptoms of malaria prevention, and treatment for malaria. Now also tested in the prevention of silicosis.
Piperaquine Phosphate is Pale yellow powder.
CAS: 4085-31-8
Molecular Formula: C29H32Cl2N6.4 H3O4P
Molecular Weight: 633.51g/mol
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Thursday 2 February 2012

The benefits of Omeprazole sulfone


Appearance of Omeprazole sulfone is White or almost white powder.
Omeprazole sulfone does have a good effect, with high efficiency and low toxicity, high cure rate, cure time is short, well tolerated, and patients easily accepted and so on. The products are proton pump inhibitors; it can directly act on the acid pump, inhibited the secretion of gastric acid, and on the HP has a killing effect.
CAS: 88546-55-8
Molecular Formula: C17H19N3O4S
Molecular Weight: 361.42g/mol
Description:It is a metabolite of omeprazole.

Tuesday 31 January 2012

How to get Hongdenafil

Hongdenafil is a white crystalline powder,odorless,bitter taste, soluble in water and
Ethanol, ramification of Sildenafil Citrate.
Hongdenafil is based on Sildenafil citrate with same mechanism of Sildenafil. Its dosage is less than Sildenafil citrate, once regarding as “untested Sildenafil”, and was test out last year by Japanese;
It has been put into the test scope by countries such as theKorea. This product should be sealed at room temperature.
CAS: 831217-01-7
Molecular Formula: C25H34N6O3
Molecular Weight: 466.583g/mol
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7-Hydroxycoumarin sulfate is for your choice

7-Hydroxycoumarin sulfate7-Hydroxycoumarin sulfate
7-Hydroxycoumarin sulfate occurs as pale yellow solid with its melting point 204-205 °C.It is a metabolite of 7-hydroxycoumarin (7-HC). It is found in hepatocyte, microsome, S9 fraction of human, dog, monkey, rat and mouse liver.This product should be stored at -70°C.
CAS: 69526-88-1
Molecular Formula: C9H5KO6S
Molecular Weight: 280.3g/mol

Monday 30 January 2012

The good effect of Midazolam

Midazolam is very good and nice.
USES:
Midazolam is used before operations or procedures to relax you, make you sleepy and to decrease your memory of the event.
Molecular Formula: C18H13ClFN3
Formula Weight:
325.77
CAS No.: 59467-64-0
Mol File:59467-64-0.mol
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Wednesday 18 January 2012

Important informations about Sodium phenylbutyrate


Sodium phenylbutyrate is a prodrug, it rapidly metabolized into acid salt. It can be combined with glutamic acid and ammonia generated phenylacetyl glutamine, through renal excretion, excretion of nitrogenous waste is another way.
Sodium Phenylbutyrate is a low molecular weight fatty acid that has been used for treatment of urea cycle disorders in children, sickle cell disease, and thalassemia.
Sodium Phenylbutyrate has been demonstrated recently that 4-PBA can act as a chemical chaperone by reducing the load of mutant or mislocated proteins retained in the endoplasmic reticulum (ER) under conditions associated with cystic fibrosis and liver injury.
CAS: 1716-12-7
Molecular Formula: C10H11O2.Na
Molecular Weight: 163.20+22.99 g/mol

The use of Ulinastatin

Ulinastatin is extracted from human urine protein, refined sugar, is a protease inhibitor. Inhibit the activity of trypsin and other trypsin effect, commonly used in the treatment of pancreatitis. In addition, the product still stable lysosomal membranes, inhibition of lysosomal enzyme release and the inhibitory effect of inhibition of cytokine production and so, therefore it can be used for emergency treatment of acute circulatory failure.
Ulinastatin is a broad-spectrum inhibitor, # 411, with inhibition for a variety of enzyme; it is used more extensive in clinical application.
Used For:
acute pancreatitis;
chronic relapsing pancreatitis;
acute circulatory failure to rescue adjuvant.

Sibutramine Suppliers


Sibutramine (usually available as sibutramine hydrochloride monohydrate) is an appetite suppressant that is administered orally for the treatment of obesity.
Sibutramine is white crystalline powder.
"Sibutramine" is a central nervous system depressants, has excited, suppressing food and so on, it might raise blood pressure, heart rate, loss of appetite, insomnia, abnormal liver function and other risk serious side effects.
Molecular Formula: C28H27NO4S
Formula Weight: 473.58
CAS No.: 106650-56-0
Mol File: 106650-56-0.mol
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Tuesday 17 January 2012

How to buy 3-O-methyldopa-d3

3-O-methyldopa-d3 is odorless White or white crystalline powder.
3-O-methyldopa-d3;3-O-methyldopa-d3;3-O-methyldopa-d3
Molecular Formula:C10H10NO4D3
Molecular Weight: 214.24 g/mol

Monday 16 January 2012

How to use Atorvastatin

Atorvastatin is an oral drug that can lower the level of cholesterol in the blood. It belongs to a class of drugs referred to as statins which includes lovastatin (Mevacor), simvastatin, (Zocor), fluvastatin (Lescol), and pravastatin (Pravachol). All statins, including atorvastatin, prevent the production of cholesterol by the liver by blocking the enzyme that makes cholesterol, HMGCoA reductase. They lower total blood cholesterol as well as LDL cholesterol levels.
Atorvastatin is the first-line lipid-lowering drugs, it is widely used in clinical practice, it is mild adverse reactions, better tolerated.
Molecular Formula: C66H68CaF2N4O10
Formula Weight: 1155.34
CAS No.: 110862-48-1
Mol File: 110862-48-1.mol
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Saturday 14 January 2012

Midazolam Suppliers

Midazolam is yellow solid,and it is an intermediate for the synthesis of Midazolam.
Midazolam;Midazolam;Midazolam
Midazolam is given to children before medical procedures or before anesthesia for surgery to cause drowsiness, relieve anxiety, and prevent any memory of the event. Midazolam is in a class of medications called benzodiazepines. It works by slowing activity in the brain to allow relaxation and sleep.
Midazolam comes as syrup to take by mouth. It is usually given as a single dose by a doctor or nurse before a medical procedure or surgery.
Molecular Formula: C18H13ClFN3
Formula Weight:
325.77
CAS No.: 59467-64-0
Mol File:59467-64-0.mol
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Friday 13 January 2012

Detailed informations of 3-O-methyldopa-d3

3-O-methyldopa-d3; 3-O-methyldopa-d3; 3-O-methyldopa-d3
3-O-methyldopa-d3 is nice and cheap abopharmachem product,welcome you to visit us and give us valuable advices.
Molecular Formula: C10H10NO4D3
Molecular Weight: 214.24 g/mol
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Thursday 12 January 2012

Where to buy Acetildenafil (Hongdenafil)


Acetildenafil (Hongdenafil) is a white crystalline powder,odorless,bitter taste, soluble in water and ethanol, ramification of Sildenafil Citrate.
Acetildenafil (Hongdenafil) is based on Sildenafil citrate with same mechanism of Sildenafil. Its dosage is less than Sildenafil citrate, once regarding as “untested Sildenafil”, and was test out last year by Japanese; it has been put into the test scope by countries such as the Korea.This product should be sealed at room temperature.
CAS: 831217-01-7
Molecular Formula: C25H34N6O3
Molecular Weight: 466.583g/mol

Wednesday 11 January 2012

The use of Aprotinin

Clinically for the prevention and treatment of acute pancreatitis, Aprotinin is used for treating bleeding caused by fibrinolysis and disseminated intravascular coagulation. Also used anti-shock treatment. In abdominal surgery, it can be directly injected into the abdominal cavity to prevent adhesions.
Aprotinin Can inhibit trypsin and chymotrypsin, prevent other active pancreatic protease activation and the original self-activation of trypsinogen.
CAS:9087-70-1
Source:Bovine Lungs
Storage:Store in an airtight, tamper-proof container, protected from light.

The introductions of Fingolimod HCl

Fingolimod HCl occurs as white solid with the melting point 102-107°C.It is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine.
Fingolimod HCl is the Drug to treat of multiple sclerosis.
Fingolimod HCl is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibitin.
CAS: 162359-56-0
Molecular Formula: C19H34ClNO2
Molecular Weight: 343.93 g/mol
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Tuesday 10 January 2012

The good effect of Latanoprost


Latanoprost is usually well tolerated, occasionally blurred vision, burning pain, tingling, conjunctival hyperemia, corneal erosion and transient point-like sense of guidance material. Some patients also appear brown iris pigmentation (6 months, 7%, after 12 months of 16%).
Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension by reducing intraocular pressure.
Latanoprost is a prostaglandin analogue (more specifically an analogue of Prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes (through the uvealsclearal tract).This product occurs as pale yellow oil.This product should be stored at -20°C.
CAS: 130209-82-4
Molecular Formula: C26H40O5
Molecular Weight: 432.59g/mol
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Monday 9 January 2012

Effect of LatanoprostLatanoprost

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension by reducing intraocular pressure. It is a prostaglandin analogue (more specifically an analogue of Prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes (through the uvealsclearal tract).This product occurs as pale yellow oil.This product should be stored at -20°C.        
Latanoprost is Pale yellow to almost colorless viscous oily.
CAS: 130209-82-4
Molecular Formula: C26H40O5
Molecular Weight: 432.59g/mol
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Saturday 7 January 2012

The function of Norfentanyl-d5


Norfentanyl-d5 is Amides and Imides; Amines and Amine Salts (excluding α-Amino Acids).
Norfentanyl-d5 should be Stored at room temperature (15-23°C).
Norfentanyl-d5 can be Stable for three years after receipt of order if stored under recommended conditions. After three years, the compound should be re-checked for chemical purity before use.
Molecular Formula: C14H15N2OD5
Molecular Weight: 237.36g/mol
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Thursday 5 January 2012

The good effect of Olmesartan medoxomil

Olmesartan medoxomil is often used as Pharmaceutical raw materials and intermediates Appearance: light yellow to white powder.
Olmesartan medoxomil's effective is better than losartan losartan and other drugs listed earlier, as an ideal anti-high blood pressure medication I, on various types of pressure have a better effect, it features a longer half-life can effective control of blood pressure in one day, so taking more convenient.
Olmesartan medoxomil occurs as white to off-white crystalline powder with the melting point 180°C .It is an angiogenesis II receptor antagonist. It can be used as an anti-hypertensive.
CAS: 144689-63-4
Molecular Formula: C24H26N6O3
Molecular Weight: 446.5g/mol
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