the uses of Dipyridamole

Dipyridamole acts as a thromboxane synthase inhibitor,consequently， lowering the levels of TXA2 and  stopping the effects of TXA2 .

Dipyridamole inhibits the cellular reabsorption of adenosine into platelets, red blood cells and endothelial cells cause increasing extracellular concentrations of adenosine.

Dipyridamole also inhibits the enzyme adenosine deaminase from  breaking down normally adenosine into inosine,which leads to further increased levels of extracellular adenosine.

Dipyridamole also inhibits the phosphodiesterase enzymes that normally break down cAMP and/or cGMP ..

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The introduction of Dipyridamole

Dipyridamole (trade name Persantine) is a drug, the thrombus formation inhibits chronic and leads to vasodilation given if given at high doses over a short period. Dipyridamole overdose can be treated with aminophylline and reverses its hemodynamic effects (vasodilation). Symptomatic treatment is recommended, possibly with vasopressor drug. Gastric lavage should be considered. Can reverse the administration of xanthine derivatives (eg aminophylline) the hemodynamic effects of dipyridamole overdose. Since dipyridamole is highly protein bound, dialysis is unlikely to be useful.
Dipyridamole was pressure.Dipyridamole pulmonary hypertension without significant decrease in systemic blood pressure and non-medical applications in the laboratory context, such as reducing the inhibition of the cardio virus growth in cell culture.
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